Total 80 clinical symptoms reported for ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder  Very Frequent (6)Uncommon (21)Occasional (39)Frequent (14)

Autistic behavior	Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior.   Synonyms:ASD; Pervasive developmental disorder	Very frequent
Delayed speech and language development	A degree of language development that is significantly below the norm for a child of a specified age.   Synonyms:Deficiency of speech development; Delayed language development; Delayed speech; Delayed speech acquisition; Delayed speech and language development; Delayed speech development; Impaired speech and language development; Impaired speech development; Language delay; Language delayed; Language development deficit; Late-onset speech development; Poor language development; Speech and language delay; Speech and language difficulties; Speech delay	Very frequent
Global developmental delay	A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age.   Synonyms:Delayed cognitive development; Delayed development; Delayed developmental milestones; Delayed intellectual development; Delayed milestones; Delayed psychomotor development; Developmental delay; Developmental delay in early childhood; Developmental delay, global; Developmental retardation; Lack of psychomotor development; Motor and developmental delay; Psychomotor delay; Psychomotor development deficiency; Psychomotor development failure; Psychomotor developmental delay; Retarded development; Retarded mental development; Retarded psychomotor development	Very frequent
Impaired social interactions	Difficulty in social interactions related to an impairment of characteristics such as eye contact, smiling, appropriate facial expressions, and body postures and characterized by difficulty in forming peer relationships and forming friendships.   Synonyms:Impaired social interaction; Impaired social interactions; Poor social interactions	Very frequent
Neurological speech impairment	Synonyms:Speech disorder; Speech impairment; Speech impediment	Very frequent
Urinary incontinence	Loss of the ability to control the urinary bladder leading to involuntary urination.   Synonyms:Bladder incontinence; Loss of bladder control	Very frequent